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Overcoming resistance to targeted therapies in NSCLC: current approaches and clinical application

The discovery that a number of aberrant tumorigenic processes and signal transduction pathways are mediated by druggable protein kinases has led to a revolutionary change in nonsmall cell lung cancer (NSCLC) treatment. Epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) are...

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Detalhes bibliográficos
Main Authors: Paolo Maione, Paola Claudia Sacco, Assunta Sgambato, Francesca Casaluce, Antonio Rossi, Cesare Gridelli
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publishing 2015-09-01
Colecção:Therapeutic Advances in Medical Oncology
Acesso em linha:https://doi.org/10.1177/1758834015595048
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