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Evaluation of Myelin Radiotracers in the Lysolecithin Rat Model of Focal Demyelination: Beware of Pitfalls!

The observation that amyloid radiotracers developed for Alzheimer’s disease bind to cerebral white matter paved the road to nuclear imaging of myelin in multiple sclerosis. The lysolecithin (lysophosphatidylcholine (LPC)) rat model of demyelination proved useful in evaluating and comparing candidate...

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Detalhes bibliográficos
Main Authors: Min Zhang, Gaëlle Hugon, Caroline Bouillot, Radu Bolbos, Jean-Baptiste Langlois, Thierry Billard, Frédéric Bonnefoi, Biao Li, Luc Zimmer, Fabien Chauveau
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi-Wiley 2019-01-01
Colecção:Contrast Media & Molecular Imaging
Acesso em linha:http://dx.doi.org/10.1155/2019/9294586
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