Molecular features evaluation of metastatic foci as the basis for metastatic breast cancer treatment personalization. Is there a place of CDK4/6-inhibitors in late-line therapy after chemotherapeutic regimens?

The problem of metastatic breast cancer treatment is linked with clonal selection both in the process of tumor evolution and under the  influence of  previous treatment. The  analysis of  metastatic niche microenvironment and the  molecular genetic features become essential for treatment individuali...

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Principais autores: A. I. Stukan, A. Y. Goryainova, E. V. Lymar, S. V. Sharov, V. V. Antipova
Formato: Artigo
Idioma:Russo
Publicado em: Remedium Group LLC 2021-12-01
coleção:Медицинский совет
Assuntos:
receptor status
metastatic focus
discordance
premetastatic niche
breast cancer
combined hormonal therapy
cdk4/6 inhibitors
Acesso em linha:https://www.med-sovet.pro/jour/article/view/6580
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