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Inflammatory mediators influence the expression of nociceptin and its receptor in human whole blood cultures.

Nociceptin/orphanin FQ and its receptor (NOP) are involved in immune responses, inflammation and pain processing. The aim of this study was to investigate the modulation of NOP and prepro-nociceptin (PNoc), the precursor of nociceptin, by inflammatory mediators in human whole blood.Peripheral blood...

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Detalhes bibliográficos
Main Authors: Lan Zhang, Frank Stuber, Ulrike M Stamer
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3774641?pdf=render
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