TNF-α promotes extracellular vesicle release in mouse astrocytes through glutaminase

Abstract Background Extracellular vesicles (EVs) are membrane-contained vesicles shed from cells. EVs contain proteins, lipids, and nucleotides, all of which play important roles in intercellular communication. The release of EVs is known to increase during neuroinflammation. Glutaminase, a mitochon...

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Main Authors: Kaizhe Wang, Ling Ye, Hongfang Lu, Huili Chen, Yanyan Zhang, Yunlong Huang, Jialin C. Zheng
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2017-04-01
Series:Journal of Neuroinflammation
Assuntos:
TNF-α
Glutaminase
Extracellular vesicles
Astrocytes
Acceso en liña:http://link.springer.com/article/10.1186/s12974-017-0853-2
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