Targeting Epigenetic Modifiers of Tumor Plasticity and Cancer Stem Cell Behavior

Tumor heterogeneity poses one of the greatest challenges to a successful treatment of cancer. Tumor cell populations consist of different subpopulations that have distinct phenotypic and genotypic profiles. Such variability poses a challenge in successfully targeting all tumor subpopulations at the...

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Bibliographic Details
Main Authors: Vigneshwari Easwar Kumar, Roshni Nambiar, Cristabelle De Souza, Audrey Nguyen, Jeremy Chien, Kit S. Lam
Format: Artigo
Language:Inglês
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
cancer stem cells
epigenetics
signaling
tumoral plasticity
inhibitors
Online Access:https://www.mdpi.com/2073-4409/11/9/1403
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