HMGB1 siRNA can reduce damage to retinal cells induced by high glucose in vitro and in vivo

Shuang Jiang, Xiaolong Chen Department of Ophthalmology, Shengjing Hospital of China Medical University, Shenyang, China Background: Diabetic retinopathy (DR), one of the most common complications of late-phase diabetes, is associated with many risk factors, among which continuous low-grade inflam...

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Detalhes bibliográficos
Main Authors: Jiang S, Chen X
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017-03-01
Colecção:Drug Design, Development and Therapy
Assuntos:
Diabetic retinopathy
Small interfering RNA
Human Retinal endothelial cells
High-mobility group box-1
Inhibitor of nuclear factor kappa-β
Nuclear factor κB
Acesso em linha:https://www.dovepress.com/hmgb1-sirna-can-reduce-damage-to-retinal-cells-induced-by-high-glucose-peer-reviewed-article-DDDT
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