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Shifting CCR7 towards Its Monomeric Form Augments CCL19 Binding and Uptake

The chemokine receptor CCR7, together with its ligands, is responsible for the migration and positioning of adaptive immune cells, and hence critical for launching adaptive immune responses. CCR7 is also induced on certain cancer cells and contributes to metastasis formation. Thus, CCR7 expression a...

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Main Authors: Oliver J. Gerken, Marc Artinger, Daniel F. Legler
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2022-04-01
Serija:Cells
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Online dostop:https://www.mdpi.com/2073-4409/11/9/1444
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