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A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection.
Host restriction factors constitute a formidable barrier for viral replication to which many viruses have evolved counter-measures. Human SAMD9, a tumor suppressor and a restriction factor for poxviruses in cell lines, is antagonized by two classes of poxvirus proteins, represented by vaccinia virus...
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Autores principales: | , , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
Public Library of Science (PLoS)
2018-02-01
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Colección: | PLoS Pathogens |
Acceso en línea: | http://europepmc.org/articles/PMC5831749?pdf=render |
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