Kynurenic Acid Inhibits the Electrical Stimulation Induced Elevated Pituitary Adenylate Cyclase-Activating Polypeptide Expression in the TNC

BackgroundMigraine is a primary headache of imprecisely known mechanism, but activation of the trigeminovascular system (TS) appears to be essential during the attack. Intensive research has recently focused on pituitary adenylate cyclase-activating polypeptide (PACAP) and the kynurenine systems as...

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Autori principali: Tamás Körtési, Bernadett Tuka, János Tajti, Teréz Bagoly, Ferenc Fülöp, Zsuzsanna Helyes, László Vécsei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018-01-01
Serie:Frontiers in Neurology
Soggetti:
migraine
trigeminovascular system
pituitary adenylate cyclase-activating polypeptide
kynurenic acid
MK-801
Accesso online:http://journal.frontiersin.org/article/10.3389/fneur.2017.00745/full
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