Phyllolobium chinense Fisch Flavonoids (PCFF) Suppresses the M1 Polarization of LPS-Stimulated RAW264.7 Macrophages by Inhibiting NF-κB/iNOS Signaling Pathway

BackgroundM1 macrophage plays an important role in inflammatory reaction. In this study, potential anti-inflammatory effect of Phyllolobium chinense Fisch flavonoids (PCFF) was assessed via Zebrafish acute inflammation model in vivo and LPS-induced pro-inflammatory M1 macrophage model in vitro.Metho...

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Bibliografiska uppgifter
Huvudupphovsmän: Hua Fan, Qiong Wu, Longping Peng, Du Li, Yidan Dong, Min Cao, Ping Liu, Xu Wang, Xudong Hu, Youhua Wang
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2020-06-01
Serie:Frontiers in Pharmacology
Ämnen:
Phyllolobium chinense Fisch flavonoids (PCFF)
zebrafish
RAW264.7 macrophages
inflammatory response
nuclear factor-κB signaling pathway
inducible nitric oxide synthases
Länkar:https://www.frontiersin.org/article/10.3389/fphar.2020.00864/full
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