Oligomerization and Ca2+/calmodulin control binding of the ER Ca2+-sensors STIM1 and STIM2 to plasma membrane lipids

Ca2+ (calcium) homoeostasis and signalling rely on physical contacts between Ca2+ sensors in the ER (endoplasmic reticulum) and Ca2+ channels in the PM (plasma membrane). STIM1 (stromal interaction molecule 1) and STIM2 Ca2+ sensors oligomerize upon Ca2+ depletion in the ER lumen, contact phosphoino...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Rajesh Bhardwaj, Hans‑Michael Müller, Walter Nickel, Matthias Seedorf
Format: Artigo
Langue:Inglês
Publié: Portland Press, Biochemical Society 2013-10-01
Collection:Bioscience Reports
Sujets:
calmodulin (CaM)
ER–PM contact site
phosphoinositides
K-rich domain
STIM2
store-operated calcium entry (SOCE)
Accès en ligne:http://www.bioscirep.org/bsr/033/e077/bsr033e077.htm
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires