ICAM-1 is a key receptor mediating cytoadherence and pathology in the Plasmodium chabaudi malaria model

Abstract Background Parasite cytoadherence within the microvasculature of tissues and organs of infected individuals is implicated in the pathogenesis of several malaria syndromes. Multiple host receptors may mediate sequestration. The identity of the host receptor(s), or the parasite ligand(s) resp...

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Main Authors: Deirdre A. Cunningham, Jing-wen Lin, Thibaut Brugat, William Jarra, Irene Tumwine, Garikai Kushinga, Jai Ramesar, Blandine Franke-Fayard, Jean Langhorne
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-05-01
Colecção:Malaria Journal
Assuntos:
Plasmodium chabaudi
Sequestration
ICAM-1
CD36
Schizont membrane-associated cytoadherence protein
SMAC
Acesso em linha:http://link.springer.com/article/10.1186/s12936-017-1834-8
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