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Challenges to the broad application of allogeneic natural killer cell immunotherapy of cancer
Abstract Natural killer (NK) cells are innate immune cells that recognize malignant cells through a wide array of germline-encoded receptors. Triggering of activating receptors results in cytotoxicity and broad immune system activation. The former is achieved through release of cytotoxic granules an...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BMC
2022-04-01
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Colecção: | Stem Cell Research & Therapy |
Assuntos: | |
Acesso em linha: | https://doi.org/10.1186/s13287-022-02769-4 |
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