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Challenges to the broad application of allogeneic natural killer cell immunotherapy of cancer

Abstract Natural killer (NK) cells are innate immune cells that recognize malignant cells through a wide array of germline-encoded receptors. Triggering of activating receptors results in cytotoxicity and broad immune system activation. The former is achieved through release of cytotoxic granules an...

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Detalhes bibliográficos
Main Authors: Philippa R. Kennedy, Martin Felices, Jeffrey S. Miller
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-04-01
Colecção:Stem Cell Research & Therapy
Assuntos:
Acesso em linha:https://doi.org/10.1186/s13287-022-02769-4
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