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Integrative analysis of breast cancer profiles in TCGA by TNBC subgrouping reveals novel microRNA-specific clusters, including miR-17-92a, distinguishing basal-like 1 and basal-like 2 TNBC subtypes

Abstract Background The term triple-negative breast cancer (TNBC) is used to describe breast cancers without expression of estrogen receptor, progesterone receptor or HER2 amplification. To advance targeted treatment options for TNBC, it is critical that the subtypes within this classification be de...

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Main Authors: Karel Kalecky, Rebecca Modisette, Samantha Pena, Young-Rae Cho, Joseph Taube
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-02-01
Colecção:BMC Cancer
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Acesso em linha:http://link.springer.com/article/10.1186/s12885-020-6600-6
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