Neuromodulation impact on nonlinear firing behavior of a reduced model motoneuron with the active dendrite

Neuromodulatory inputs from brainstem systems modulate the normal function of spinal motoneurons by altering the activation properties of persistent inward currents (PICs) in their dendrites. However, the effect of the PIC on firing outputs also depends on its location in the dendritic tree. To inve...

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Hlavní autoři: Hojeong eKim, CJ eHeckman
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014-09-01
Edice:Frontiers in Computational Neuroscience
Témata:
Computer Simulation
Neuromodulation
motoneurons
nonlinear firing
persistent inward current
reduced modeling
On-line přístup:http://journal.frontiersin.org/Journal/10.3389/fncom.2014.00110/full
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