Δ9-tetrahydrocannabinol prevents methamphetamine-induced neurotoxicity.

Methamphetamine (METH) is a potent psychostimulant with neurotoxic properties. Heavy use increases the activation of neuronal nitric oxide synthase (nNOS), production of peroxynitrites, microglia stimulation, and induces hyperthermia and anorectic effects. Most METH recreational users also consume c...

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Auteurs principaux: M Paola Castelli, Camilla Madeddu, Alberto Casti, Angelo Casu, Paola Casti, Maria Scherma, Liana Fattore, Paola Fadda, M Grazia Ennas
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2014-01-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC4028295?pdf=render
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