Clarithromycin and endoscopic sinus surgery for adults with chronic rhinosinusitis with and without nasal polyps: study protocol for the MACRO randomised controlled trial

Abstract Background Chronic rhinosinusitis (CRS) is a common source of ill health; 11% of UK adults reported CRS symptoms in a worldwide population study. Guidelines are conflicting regarding whether antibiotics should be included in primary medical management, reflecting the lack of evidence in sys...

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Hauptverfasser: Carl Philpott, Steffi le Conte, David Beard, Jonathan Cook, William Sones, Steve Morris, Caroline S. Clarke, Mike Thomas, Paul Little, Jane Vennik, Valerie Lund, Helen Blackshaw, Anne Schilder, Stephen Durham, Spiros Denaxas, James Carpenter, James Boardman, Claire Hopkins, On behalf of the MACRO programme team
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2019-04-01
Schriftenreihe:Trials
Schlagworte:
chronic rhinosinusitis
endoscopic sinus surgery
clarithromycin
randomised controlled trial
Online Zugang:http://link.springer.com/article/10.1186/s13063-019-3314-7
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