Development of the Digital Arthritis Index, a Novel Metric to Measure Disease Parameters in a Rat Model of Rheumatoid Arthritis

Despite a broad spectrum of anti-arthritic drugs currently on the market, there is a constant demand to develop improved therapeutic agents. Efficient compound screening and rapid evaluation of treatment efficacy in animal models of rheumatoid arthritis (RA) can accelerate the development of clinica...

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Detalhes bibliográficos
Main Authors: Maria A. Lim, Brenton Louie, Daniel Ford, Kyle Heath, Paulyn Cha, Joe Betts-Lacroix, Pek Yee Lum, Timothy L. Robertson, Laura Schaevitz
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017-11-01
Colecção:Frontiers in Pharmacology
Assuntos:
phenotypic screening
drug discovery screening
rheumatoid arthritis (RA)
collagen induced arthritis
continuous monitoring platforms
rodent models of disease
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fphar.2017.00818/full
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