Localized delivery of therapeutic doxorubicin dose across the canine blood–brain barrier with hyperthermia and temperature sensitive liposomes

Most drugs cannot penetrate the blood–brain barrier (BBB), greatly limiting the use of anti-cancer agents for brain cancer therapy. Temperature sensitive liposomes (TSL) are nanoparticles that rapidly release the contained drug in response to hyperthermia (>40 °C). Since hyperthermia also transie...

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Detaylı Bibliyografya
Asıl Yazarlar: Amy Lee Bredlau, Anjan Motamarry, Chao Chen, M. A. McCrackin, Kris Helke, Kent E. Armeson, Katrina Bynum, Ann-Marie Broome, Dieter Haemmerich
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis Group 2018-01-01
Seri Bilgileri:Drug Delivery
Konular:
thermosensitive liposomes
thermal therapy
blood–brain barrier
hyperthermia
doxorubicin
liposomes
Online Erişim:http://dx.doi.org/10.1080/10717544.2018.1461280
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