WAKE-mediated modulation of cVA perception via a hierarchical neuro-endocrine axis in Drosophila male-male courtship behaviour

The authors show that the Drosophila master regulator WAKE modulates the secretion of insulin-like peptides, triggering a decrease in 20-hydroxyecdysone levels. This lowers the perception of a male-specific sex pheromone and explains why WAKE-deficient Drosophila flies show male-male courtship behav...

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Main Authors: Shiu-Ling Chen, Bo-Ting Liu, Wang-Pao Lee, Sin-Bo Liao, Yao-Bang Deng, Chia-Lin Wu, Shuk-Man Ho, Bing-Xian Shen, Guan-Hock Khoo, Wei-Chiang Shiu, Chih-Hsuan Chang, Hui-Wen Shih, Jung-Kun Wen, Tsuo-Hung Lan, Chih-Chien Lin, Yu-Chen Tsai, Huey-Fen Tzeng, Tsai-Feng Fu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2022-05-01
Colecção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-022-30165-2
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