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Molecular Rescue of Dyrk1A Overexpression Alterations in Mice with Fontup<sup>®</sup> Dietary Supplement: Role of Green Tea Catechins
Epigallocatechin gallate (EGCG) is an inhibitor of DYRK1A, a serine/threonine kinase considered to be a major contributor of cognitive dysfunctions in Down syndrome (DS). Two clinical trials in adult patients with DS have shown the safety and efficacy to improve cognitive phenotypes using commercial...
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Hauptverfasser: | , , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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MDPI AG
2020-02-01
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Schriftenreihe: | International Journal of Molecular Sciences |
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Online Zugang: | https://www.mdpi.com/1422-0067/21/4/1404 |
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