Association between ankylosing spondylitis and the miR-146a and miR-499 polymorphisms.

miRNAs are small, non-coding RNAs that regulate the expression of multiple target genes at the post-transcriptional level. Single-nucleotide polymorphisms (SNPs) in miRNA sequences may alter miRNA expression and have been implicated in the pathogenesis of multiple forms of arthritis, including rheum...

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Autori principali: Hui Ying Xu, Zhang Yang Wang, Jing Feng Chen, Tian Yang Wang, Ling Ling Wang, Li Li Tang, Xian-yang Lin, Chun-wu Zhang, Bi-cheng Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2015-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC4383612?pdf=render
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