Vaccination inducing durable and robust antigen-specific Th1/Th17 immune responses contributes to prophylactic protection against Mycobacterium avium infection but is ineffective as an adjunct to antibiotic treatment in chronic disease

Mycobacterium avium complex (MAC) causing pulmonary disease in humanshas emerged worldwide. Thus, effective strategies simultaneously aiming to prevent MAC infection and accelerate therapeutic efficacy are required. To this end, subunit vaccine-induced protection against a well-defined virulent Myco...

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Main Authors: Ju Mi Lee, Jiyun Park, Steven G Reed, Rhea N Coler, Jung Joo Hong, Lee-Han Kim, Wonsik Lee, Kee Woong Kwon, Sung Jae Shin
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2022-12-01
Serier:Virulence
Fag:
Mycobacterium avium complex
Immunogenicity
Subunit vaccine
Preventative vaccine
Therapeutic vaccine
Online adgang:https://www.tandfonline.com/doi/10.1080/21505594.2022.2068489
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