Pleiotropic effects of a methyl donor diet in a novel animal model.

Folate and other methyl-donor pathway components are widely supplemented due to their ability to prevent prenatal neural tube defects. Several lines of evidence suggest that these supplements act through epigenetic mechanisms (e.g. altering DNA methylation). Primary among these are the experiments o...

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Autores principales: Kimberly R Shorter, Vanessa Anderson, Patricia Cakora, Amy Owen, Keswick Lo, Janet Crossland, April C H South, Michael R Felder, Paul B Vrana
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2014-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC4133251?pdf=render
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