Pleiotropic effects of a methyl donor diet in a novel animal model.

Folate and other methyl-donor pathway components are widely supplemented due to their ability to prevent prenatal neural tube defects. Several lines of evidence suggest that these supplements act through epigenetic mechanisms (e.g. altering DNA methylation). Primary among these are the experiments o...

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Autori principali: Kimberly R Shorter, Vanessa Anderson, Patricia Cakora, Amy Owen, Keswick Lo, Janet Crossland, April C H South, Michael R Felder, Paul B Vrana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC4133251?pdf=render
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