N-Monosubstituted Methoxy-oligo(ethylene glycol) Carbamate Ester Prodrugs of Resveratrol

Resveratrol is a natural polyphenol with many interesting biological activities. Its pharmacological exploitation in vivo is, however, hindered by its rapid elimination via phase II conjugative metabolism at the intestinal and, most importantly, hepatic levels. One approach to bypass this problem re...

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Bibliographische Detailangaben
Hauptverfasser: Andrea Mattarei, Michele Azzolini, Mario Zoratti, Lucia Biasutto, Cristina Paradisi
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2015-09-01
Schriftenreihe:Molecules
Schlagworte:
resveratrol
prodrugs
methoxy-oligo(ethylene glycol)
poly(ethylene glycol)
polyphenols
bioavailability
carbamate ester
Online Zugang:http://www.mdpi.com/1420-3049/20/9/16085
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