lncRNA TUG1 modulates proliferation, apoptosis, invasion, and angiogenesis via targeting miR-29b in trophoblast cells

Abstract Background Pre-eclampsia (PE) is regarded as the leading cause of maternal and neonatal morbidity and mortality. Nevertheless, the potential mechanism for the regulation of trophoblast behaviors and the pathogenesis of PE remain largely elusive. Recently, accumulating evidence emphasized th...

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Bibliographic Details
Main Authors: Qian Li, Jing Zhang, Dong-Mei Su, Li-Na Guan, Wei-Hong Mu, Mei Yu, Xu Ma, Rong-Juan Yang
Format: Artigo
Language:Inglês
Published: BMC 2019-09-01
Series:Human Genomics
Subjects:
Pre-eclampsia
lncRNA TUG1
miR-29b
MCL1
VEGFA
MMP2
Online Access:http://link.springer.com/article/10.1186/s40246-019-0237-z
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