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Cyclin-Dependent Kinase Inhibitors as Marketed Anticancer Drugs: Where Are We Now? A Short Survey

In the early 2000s, the anticancer drug imatinib (Glivec®) appeared on the market, exhibiting a new mode of action by selective kinase inhibition. Consequently, kinases became a validated therapeutic target, paving the way for further developments. Although these kinases have been thoroughly studied...

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Detalhes bibliográficos
Main Authors: Gaëlle Mariaule, Philippe Belmont
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2014-09-01
Colecção:Molecules
Assuntos:
CDK
Acesso em linha:http://www.mdpi.com/1420-3049/19/9/14366
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