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Assessment of targeted and non-targeted responses in cells deficient in ATM function following exposure to low and high dose X-rays.

Radiation sensitivity at low and high dose exposure to X-rays was investigated by means of chromosomal aberration (CA) analysis in heterozygous ATM mutation carrier and A-T patient (biallelic ATM mutation) lymphoblastoid cell lines (LCLs). Targeted and non-targeted responses to acutely delivered irr...

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Detalhes bibliográficos
Main Authors: Anne Kiuru, Meerit Kämäräinen, Sirpa Heinävaara, Katri Pylkäs, Kim Chapman, Armi Koivistoinen, Teuvo Parviainen, Robert Winqvist, Munira Kadhim, Virpi Launonen, Carita Lindholm
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2014-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3969311?pdf=render
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