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IL-22 mediates goblet cell hyperplasia and worm expulsion in intestinal helminth infection.

Type 2 immune responses are essential in protection against intestinal helminth infections. In this study we show that IL-22, a cytokine important in defence against bacterial infections in the intestinal tract, is also a critical mediator of anti-helminth immunity. After infection with Nippostrongy...

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Auteurs principaux: Jan-Eric Turner, Brigitta Stockinger, Helena Helmby
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2013-01-01
Collection:PLoS Pathogens
Accès en ligne:http://europepmc.org/articles/PMC3795034?pdf=render
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