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Urea amidolyase (DUR1,2) contributes to virulence and kidney pathogenesis of Candida albicans.

The intracellular enzyme urea amidolyase (Dur1,2p) enables C. albicans to utilize urea as a sole nitrogen source. Because deletion of the DUR1,2 gene reduces survival of C. albicans co-cultured with a murine macrophage cell line, we investigated the role of Dur1,2p in pathogenesis using a mouse mode...

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Bibliografische gegevens
Hoofdauteurs: Dhammika H M L P Navarathna, Michail S Lionakis, Martin J Lizak, Jeeva Munasinghe, Kenneth W Nickerson, David D Roberts
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2012-01-01
Reeks:PLoS ONE
Online toegang:http://europepmc.org/articles/PMC3483220?pdf=render
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