Nimotuzumab Combined With Irradiation Enhances the Inhibition to the HPV16 E6-Promoted Growth of Cervical Squamous Cell Carcinoma

Human papillomavirus (HPV) 16 E6 has been proved to increase the radiosensitivity and lead to the EGFR overexpression in cervical cancer cells. In this study, to investigate the inhibition of nimotuzumab-mediated EGFR blockade combined with radiotherapy, we established a C33A cervical squamous cell...

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Auteurs principaux: Zhonghua Xu, Hang Shu, Fan Zhang, Weiwei Luo, Yan Li, Jinjin Chu, Qihong Zhao, Yin Lv
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020-08-01
Collection:Frontiers in Oncology
Sujets:
cervical squamous cell carcinoma
human papillomavirus
epidermal growth factor receptor
nimotuzumab
radiosensitivity
Accès en ligne:https://www.frontiersin.org/article/10.3389/fonc.2020.01327/full
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