Single-Nucleus Sequencing of an Entire Mammalian Heart: Cell Type Composition and Velocity

Analyses on the cellular level are indispensable to expand our understanding of complex tissues like the mammalian heart. Single-nucleus sequencing (snRNA-seq) allows for the exploration of cellular composition and cell features without major hurdles of single-cell sequencing. We used snRNA-seq to i...

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Bibliographic Details
Main Authors: Markus Wolfien, Anne-Marie Galow, Paula Müller, Madeleine Bartsch, Ronald M. Brunner, Tom Goldammer, Olaf Wolkenhauer, Andreas Hoeflich, Robert David
Format: Artigo
Language:Inglês
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
snrna-seq
rna velocity
cluster analysis
cardiomyocytes
seurat
Online Access:https://www.mdpi.com/2073-4409/9/2/318
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