MicroRNAs as diagnostic and therapeutic tools for Alzheimer’s disease: advances and limitations

Alzheimer’s disease (AD) is the most common age-related, progressive neurodegenerative disease. It is characterized by memory loss and cognitive decline and responsible for most cases of dementia in the elderly. Late-onset or sporadic AD accounts for > 95% of cases, with age at onset > 65 year...

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Detalhes bibliográficos
Main Authors: Bridget Martinez, Philip V Peplow
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Medknow Publications 2019-01-01
Colecção:Neural Regeneration Research
Assuntos:
Alzheimer′s disease; mild cognitive impairment; microRNAs; biomarkers; blood; brain tissue; cerebrospinal fluid; humans; animal models
Acesso em linha:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=2;spage=242;epage=255;aulast=Martinez
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