Ethnic differences in ApoC-III concentration and the risk of cardiovascular disease: No evidence for the cardioprotective role of rare/loss of function APOC3 variants in non-Europeans

Background: Hypertriglyceridemia is as an independent risk factor for cardiovascular disease (CVD). Apolipoprotein C-III (ApoC-III) is known to regulate triglyceride (TG) metabolism. However, the causal association between ApoC-III and CVD development is unclear. The objectives were to examine the i...

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Main Authors: Madhusmita Rout, Megan Lerner, Piers R. Blackett, Marvin D. Peyton, Stavros Stavrakis, Evgeny Sidorov, Dharambir K. Sanghera
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2022-01-01
Series:American Heart Journal Plus
Assuntos:
Circulating triglycerides
Apolipoprotein C-III concentration
Lipid metabolites
Rare variants
Ethnicity
Cardiovascular disease
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2666602222000453
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