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The Ethanol Extract of Fructus trichosanthis Promotes Fetal Hemoglobin Production via p38 MAPK Activation and ERK Inactivation in K562 Cells

Pharmacological stimulation of fetal hemoglobin (HbF) expression may be a promising approach for the treatment of beta-thalassemia. In this study, the effects of Fructus trichosanthis (FT) were investigated in human erythroleukemic K562 cells for their gamma-globin mRNA and HbF-induction activities....

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Detalhes bibliográficos
Main Authors: Hui Li, Chun Hay Ko, Suk Ying Tsang, Ping Chung Leung, Ming Chui Fung, Kwok Pui Fung
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Limited 2011-01-01
Colecção:Evidence-Based Complementary and Alternative Medicine
Acesso em linha:http://dx.doi.org/10.1093/ecam/neq022
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