Opioid Drug-Drug-Drug Interactions and Unintentional Traumatic Injury: Screening to Detect Three-Way Drug Interaction Signals

Growing evidence suggests that drug interactions may be responsible for much of the known association between opioid use and unintentional traumatic injury. While prior research has focused on pairwise drug interactions, the role of higher-order (i.e., drug-drug-drug) interactions (3DIs) has not bee...

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Detalhes bibliográficos
Main Authors: Emily K. Acton, Sean Hennessy, Colleen M. Brensinger, Warren B. Bilker, Todd A. Miano, Sascha Dublin, John R. Horn, Sophie Chung, Douglas J. Wiebe, Allison W. Willis, Charles E. Leonard
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Pharmacology
Assuntos:
drug interactions
injury
opioid analgesics
pharmacoepidemiology
population health
self-controlled case series
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2022.845485/full
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