Opioid Drug-Drug-Drug Interactions and Unintentional Traumatic Injury: Screening to Detect Three-Way Drug Interaction Signals

Growing evidence suggests that drug interactions may be responsible for much of the known association between opioid use and unintentional traumatic injury. While prior research has focused on pairwise drug interactions, the role of higher-order (i.e., drug-drug-drug) interactions (3DIs) has not bee...

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Détails bibliographiques
Auteurs principaux: Emily K. Acton, Sean Hennessy, Colleen M. Brensinger, Warren B. Bilker, Todd A. Miano, Sascha Dublin, John R. Horn, Sophie Chung, Douglas J. Wiebe, Allison W. Willis, Charles E. Leonard
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2022-05-01
Collection:Frontiers in Pharmacology
Sujets:
drug interactions
injury
opioid analgesics
pharmacoepidemiology
population health
self-controlled case series
Accès en ligne:https://www.frontiersin.org/articles/10.3389/fphar.2022.845485/full
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