Inorganic Polyphosphate Is Essential for Salmonella Typhimurium Virulence and Survival in Dictyostelium discoideum

Inorganic polyphosphate (polyP) deficiency in enteric bacterial pathogens reduces their ability to invade and establish systemic infections in different hosts. For instance, inactivation of the polyP kinase gene (ppk) encoding the enzyme responsible for polyP biosynthesis reduces invasiveness and in...

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Main Authors: Macarena A. Varas, Sebastián Riquelme-Barrios, Camila Valenzuela, Andrés E. Marcoleta, Camilo Berríos-Pastén, Carlos A. Santiviago, Francisco P. Chávez
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-01-01
Colecção:Frontiers in Cellular and Infection Microbiology
Assuntos:
Salmonella
Dictyostelium
polyphosphate
ppk
virulence
intracellular survival
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fcimb.2018.00008/full
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