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Deletion of miR-126a Promotes Hepatic Aging and Inflammation in a Mouse Model of Cholestasis
MicroRNAs (miRNAs) act as regulators of aging at the tissue or organism level or as regulators of cellular senescence. Targeted deletion of miR-126 in mice causes partial embryonic lethality, but its biological function in the liver is still largely unknown. Here, we deleted miR-126a, using the CRIS...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019-06-01
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| Colecção: | Molecular Therapy: Nucleic Acids |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2162253119300757 |
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