The Role of Immune Checkpoint Receptors in Regulating Immune Reactivity in Lupus

Immune checkpoint receptors with co-stimulatory and co-inhibitory signals are important modulators for the immune system. However, unrestricted co-stimulation and/or inadequate co-inhibition may cause breakdown of self-tolerance, leading to autoimmunity. Systemic lupus erythematosus (SLE) is a compl...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kun-Lin Lu, Ming-Ying Wu, Chi-Hui Wang, Chuang-Wei Wang, Shuen-Iu Hung, Wen-Hung Chung, Chun-Bing Chen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2019-10-01
Cyfres:Cells
Pynciau:
autoimmunity
co-stimulatory signals
co-inhibitory signals
immune checkpoint
immune regulation
immune-related adverse events
systemic lupus erythematosus
Mynediad Ar-lein:https://www.mdpi.com/2073-4409/8/10/1213
Tagiau: Ychwanegu Tag
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