Curcumin Protects against CCl4-Induced Liver Fibrosis in Rats by Inhibiting HIF-1α Through an ERK-Dependent Pathway

The ERK/HIF-1α signaling pathway is believed to play an important role in the genesis of progressive fibrosis. An increasing expression of HIF-1α and ERK accompanies CCl4-induced liver fibrosis in rats. Curcumin is verified to have antifibrotic effects in several kinds of liver fibrosis models....

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Yanling Zhao, Xiao Ma, Jiabo Wang, Xuan He, Yan Hu, Ping Zhang, Ruilin Wang, Ruisheng Li, Man Gong, Shengqiang Luo, Xiaohe Xiao
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2014-11-01
Serija:Molecules
Teme:
curcumin
carbon tetrachloride
liver fibrosis
hypoxia inducible factor
Online dostop:http://www.mdpi.com/1420-3049/19/11/18767
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki