New perspective on dextran sodium sulfate colitis: antigen-specific T cell development during intestinal inflammation.

CD4+ T cell responses against oral antigens can develop in inflammatory bowel disease (IBD) patients, which may modulate disease. Dextran sodium sulfate (DSS) colitis is commonly used to study IBD, however, it is not considered the best model in which to study T cell involvement in intestinal diseas...

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Main Authors: Mary E Morgan, Bin Zheng, Pim J Koelink, Hendrick J G van de Kant, Lizette C J M Haazen, Manon van Roest, Johan Garssen, Gert Folkerts, Aletta D Kraneveld
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2013-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3723715?pdf=render
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