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Exploration of novel ligands to target C-C Motif Chemokine Receptor 2 (CCR2) as a promising pharmacological treatment against traumatic brain injury

It is widely reported that the overexpression of the C-C Motif Chemokine Receptor 2 (CCR2) has negative implications in neuroinflammatory diseases such as traumatic brain injury (TBI), although promising drugs to tackle this have been less forthcoming. As of 2016, only 2 drugs specifically targeting...

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Main Authors: Kilian R. Sachdev, Kevin J. Lynch, George E. Barreto
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-07-01
Colecção:Biomedicine & Pharmacotherapy
Assuntos:
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0753332222005443
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