Development of a benchmark dose for lead-exposure based on its induction of micronuclei, telomere length changes and hematological toxicity

Background: Excessive lead exposure is associated with adverse health effects. However, there is a lack of systematic investigation using large populations to ascertain acceptable exposure limits. Objectives: Our study was aimed to identify human exposure–response relationships between lead exposure...

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Detalhes bibliográficos
Main Authors: Tuanwei Wang, Yuting Tu, Guanghui Zhang, Shiyang Gong, Kan Wang, Yunxia Zhang, Yu Meng, Tongshuai Wang, Anqi Li, David C. Christiani, William Au, Yiliang Zhu, Zhao-lin Xia
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-12-01
Colecção:Environment International
Assuntos:
Lead exposure
Hematological parameter
Micronuclei
Telomere length
Restricted cubic splines
Benchmark dose
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0160412020320845
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