Dual Effect of Soloxolone Methyl on LPS-Induced Inflammation In Vitro and In Vivo

Plant-extracted triterpenoids belong to a class of bioactive compounds with pleotropic functions, including antioxidant, anti-cancer, and anti-inflammatory effects. In this work, we investigated the anti-inflammatory and anti-oxidative activities of a semisynthetic derivative of 18βH-glycyrrhetinic...

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Main Authors: Andrey V. Markov, Aleksandra V. Sen’kova, Valeriya O. Babich, Kirill V. Odarenko, Vadim A. Talyshev, Oksana V. Salomatina, Nariman F. Salakhutdinov, Marina A. Zenkova, Evgeniya B. Logashenko
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-10-01
Colecção:International Journal of Molecular Sciences
Assuntos:
18βH-glycyrrhetinic acid
derivatives
soloxolone methyl
anti-inflammatory activity
cytokines production
LPS-induced endotoxemia
Acesso em linha:https://www.mdpi.com/1422-0067/21/21/7876
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