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The probiotic mixture VSL#3 dampens LPS-induced chemokine expression in human dendritic cells by inhibition of STAT-1 phosphorylation.

VSL#3, a mixture of 8 different probiotic bacteria, has successfully been used in the clinic to treat Ulcerative Colitis. We previously identified the modulation of chemokines as a major mechanism in the protective effect of the VSL#3 in a mouse model of colitis. This was supported by in vitro studi...

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Hlavní autoři: Rob Mariman, Frans Tielen, Frits Koning, Lex Nagelkerken
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2014-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC4278714?pdf=render
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