MTMR2 promotes invasion and metastasis of gastric cancer via inactivating IFNγ/STAT1 signaling

Abstract Background The aberrant expression of myotubularin-related protein 2 (MTMR2) has been found in some cancers, but little is known about the roles and clinical relevance. The present study aimed to investigate the roles and clinical relevance of MTMR2 as well as the underlying mechanisms in g...

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Detalhes bibliográficos
Main Authors: Lei Jiang, Jun-yan Liu, Yan Shi, Bo Tang, Tao He, Jia-jia Liu, Jun-yan Fan, Bin Wu, Xian-hui Xu, Yong-liang Zhao, Feng Qian, You-hong Cui, Pei-wu Yu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-05-01
Colecção:Journal of Experimental & Clinical Cancer Research
Assuntos:
Myotubularin-related protein 2
Gastric cancer
Invasion
Epithelial- mesenchymal transition (EMT)
IFNγ/STAT1 signaling
Acesso em linha:http://link.springer.com/article/10.1186/s13046-019-1186-z
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