Chondroprotective Effects and Mechanisms of Dextromethorphan: Repurposing Antitussive Medication for Osteoarthritis Treatment

Osteoarthritis (OA) is the most common joint disorder and primarily affects older people. The ideal anti-OA drug should have a modest anti-inflammatory effect and only limited or no toxicity for long-term use. Because the antitussive medication dextromethorphan (DXM) is protective in atherosclerosis...

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Detaylı Bibliyografya
Asıl Yazarlar: Liv Weichien Chen, Feng-Cheng Liu, Li-Feng Hung, Chuan-Yueh Huang, Shiu-Bii Lien, Leou-Chyr Lin, Jenn-Haung Lai, Ling-Jun Ho
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2018-03-01
Seri Bilgileri:International Journal of Molecular Sciences
Konular:
dextromethorphan
osteoarthritis
chondrocyte
MMP-13
collagen-induced arthritis
Online Erişim:http://www.mdpi.com/1422-0067/19/3/825
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